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Cascade-catalysed nanocarrier degradation for regulating metabolism homeostasis and enhancing drug penetration on breast cancer

Abstract The abnormal structure of tumor vascular seriously hinders the delivery and deep susanne kaufmann vitamin c complex penetration of drug in tumor therapy.Herein, an integrated and tumor microenvironment (TME)-responsive nanocarrier is designed, which can dilate vessle and improve the drug penetration by in situ releasing nitric oxide (NO).B

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